Post Cycle Therapy


42.00 USD  

Manufacturer: Kalpa Pharmaceuticals, India
Substance: Exemestane
Pack: 30 tabs (25 mg/tab)

Buy 5+ for 39.90 USD and save 10.50 USD


Aromaxyl (Exemestane)

Aromaxyl (Exemestane) is a steroidal suicide aromatase inhibitor. It is very similar in structure and action toformestane, although it is significantly more potent in comparison. As a class of drugs, aromataseinhibitors offer an anti-estrogenic effect by blocking the enzyme responsible for synthesizingestrogens. Exemestane is approved by the FDA for the treatment of breast cancer in women, specifically in post-menopausal patients whose cancer has progressed following therapy with tamoxifen. Male bodybuilders and athletes often use the drug for non-approved purposes, namely tocounter the estrogenic side effects associated with the use of aromatizable anabolic/androgenicsteroids. This may include gynecomastia, fat buildup, and water retention. In some instancesaromatase inhibitors may also assist this group with the loss of body fat and increases in musculardefinition. Exemestane is one of the most potent aromatase inhibitors presently available. The mostcommonly cited data (found in the Aromasin packaging insert) reports a lowering of serum estrogenlevels by 85% on average in clinical studies with women. Exemestane is classified as an irreversible steroidal aromatase inhibitor. It has the chemicaldesignation 6-methyl-enandrosta-1,4-diene-3,17-dione.


Exemestane is FDA approved for adjunctive treatment of postmenopausal women with estrogen-receptor positive early breast cancer with disease progression following tamoxifen. Therapy isinitiated 2-3 years after tamoxifen has failed to elicit a desirable response, at which point tamoxifenis discontinued. Treatment with exemestane is continued for 2-3 additional years, and is completedafter 5 years of cumulative adjunctive drug therapy (tamoxifen and exemestane treatment combined).The dosage prescribed in all instances is one 25 mg tablet per day, taken after a meal. When used tomitigate the estrogenic side effects of anabolic/androgenic steroid use or increase muscle definition,male athletes and bodybuilders will commonly take 12.5 mg to 25 mg of exemestane per day. In someinstances a half of a tablet (12.5 mg) taken every other day is sufficient to prevent the onset ofestrogenic side effects.

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